It depends on who you tend to assassinate and how much people know about it.
If you come to town and basically let it be known that you're a killer for hire, it won't sit well. That might seem obvious, but in some game worlds that sort of thing is okay, so I'm just putting out there to be clear.
If it's just your skillset (your 'way') and people don't get the impression that you'll just knife anyone for the right price, then you can fit in easily. Whether or not you really will knife anyone for the right price doesn't matter so much as whether people
think that.
Also, there is an active rogue's guild, and her character can find both guidance and work opportunities through them. Her character can also find herself in a ditch if she crosses them, but, I'm sure she could figure that part out...